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PMWS研究文档
发表于Mar 2007: Journal of Comparative PathologyVaccination of Porcine Circovirus type 2 (PCV2)-infected Sows against Porcine Parvovirus (PPV) and Erysipelas: Effect on Post-weaning Multisystemic Wasting Syndrome (PMWS) and on PCV2 Genome Load in the Offspring
N. Rose, P. Blanchard, R. Cariolet, B. Grasland, N. Amenna, A. Oger, B. Durand, M. Balasch, A. Jestin and F. Madec
The effect of different Parvovirus+Erysipelas vaccination schemes in PCV2-infected sows on PMWS outcome in the offspring was investigated under experimental conditions. Six PCV2-free sows were first infected oro-nasally with PCV2 two months before insemination...
发表于Jan 2007: Virology - Volume 357, Issue 2 , 20 January 2007, Pages 175-185
Molecular evolution of porcine circovirus type 2 genomes: Phylogeny and clonality
A. Olvera, M. Cortey and J. Segalés
Porcine circoviruses (PCVs) type 1 (PCV1) and type 2 (PCV2) show high levels of nucleotide similarity, but PCV1 is considered non-pathogenic and PCV2 has been associated with several disease outcomes in pigs, mainly postweaning multisystemic wasting syndrome...
发表于Jan 2007: Veterinary Microbiology - Volume 119, Issues 2-4 , 31 January 2007, Pages 97-104
Generation and immunogenicity of a recombinant pseudorabies virus expressing cap protein of porcine circovirus type 2
Yunfeng Songa, Meilin Jina, Songlin Zhang, Xiaojuan Xu, Shaobo Xiao, Shengbo Cao and Huanchun Chena
Porcine circovirus type 2 (PCV2) is associated with post-weaning multisystemic wasting syndrome (PMWS), which is an important economical disease affecting the pig industry worldwide. In order to develop an effective vaccine for PMWS, a recombinant pseudorabies...
发表于Dec 2006: Australian Veterinary Journal, Volume 84, Number 12, December 2006, pp. 421-425(5)
Genetic characterisation of Australian strains of porcine circovirus types 1 and 2
Muhling, J; Raye, WS; Buddle, JR; Wilcox, GE
Objective As post-weaning multi-systemic wasting syndrome (PMWS) has not been identified within Australia, to determine if the absence of disease was associated with genetic differences between the strains of porcine circovirus (PCV) present in...
发表于Dec 2006: Vet Microbiol. 2006 Dec 9; [Epub ahead of print]
Protection of pigs against post-weaning multisystemic wasting syndrome by a recombinant adenovirus expressing the capsid protein of porcine circovirus type 2.
Wang X, Jiang P, Li Y, Jiang W, Dong X.
Post-weaning multisystemic wating syndrome (PMWS) associated with PCV2 was one of the most costly diseases currently faced by the swine industry. In order to develop a vaccine to control this disease, we previously constructed a recombinant adenovirus...
发表于Dec 2006: Vet Rec. 2006 Dec 2;159(23):761-8.
Survey of pigs' kidneys with lesions consistent with PMWS and PDNS and ochratoxicosis. Part 2: pathological and histological findings.
Gresham A, Done S, Livesey C, Macdonald S, Chan D, Sayers R, Clark C, Kemp P.
One thousand condemned pigs' kidneys were collected in February 2002 from two pig abattoirs in England to assess the lesions due to postweaning multisystemic wasting syndrome (pmws) and porcine dermatitis and nephropathy syndrome (pdns) and the possible...
发表于Dec 2006: Dev Biol (Basel). 2006;126:107-13; discussion 325-6.
Swine and circovirus.
Banks M, Grierson S, Tucker D, Bailey M, Donadeau M, Sargent C, King D, Mellencamp M.
In the 1990s Post-weaning, multi-systemic wasting syndrome (PMWS) emerged in N. America and Europe as a major disease problem with significant welfare and economic consequences for pig producers. The disease, characterised by wasting, respiratory, enteric...
发表于Dec 2006: J Swine Health Prod 2006;14(3):133-139
Effects of adjuvants on porcine circovirus type 2-associated lesions
Marlin J. Hoogland, DVM, MS; Tanja Opriessnig, Dr med vet; Patrick G. Halbur, DVM, PhD
Objective: To determine if adjuvants differ in their ability to trigger lesions associated with porcine circovirus type 2 (PCV2). Methods: Ninety pigs randomly assigned to five groups were vaccinated intramuscularly at 4 and 6 weeks...
发表于Nov 2006: Vet Pathol. 2006 Nov;43(6):993-7
Immunohistochemical MHC-II and interleukin 2-R (CD25) expression in lymph nodes of pigs with spontaneous postweaning multisystemic wasting syndrome (PMWS).
Mandrioli L, Sarli G, Zengarini M, Panarese S, Marcato PS.
Immunohistochemical expression of immunocompetent cells bearing major histocompatibility complex (MHC-II) and interleukin 2-R (IL2-R) (CD25) molecules was performed on lymph nodes with spontaneous postweaning multisystemic wasting syndrome (PMWS). Control...
发表于Nov 2006: J Gen Virol. 2006 Nov;87(Pt 11):3215-23.
Porcine circovirus type 2 replicase binds the capsid protein and an intermediate filament-like protein.
Timmusk S, Fossum C, Berg M.
Porcine circovirus type 2 (PCV2) is an important porcine pathogen that establishes persistent subclinical infections but may, on activation, contribute to the development of post-weaning multisystemic wasting syndrome (PMWS). This disease is characterized...
发表于Oct 2006: Research in Veterinary Science - Available online 24 October 2006
Sow porcine circovirus type 2 (PCV2) status effect on litter mortality in postweaning multisystemic wasting syndrome (PMWS)
M. Calsamiglia, L. Fraile, A. Espinal, A. Cuxart, C. Seminati, M. Martína,, E. Mateua,, M. Domingo and J. Segalés
Previous studies have described a “litter effect” associated with mortality in postweaning multisystemic wasting syndrome (PMWS) affected farms. The main objective of this study was to evaluate litter mortality in different PMWS affected farms and to...
发表于Oct 2006: Immunology. 2006 Oct 13; [Epub ahead of print]
Silencing of natural interferon producing cell activation by porcine circovirus type 2 DNA.
Vincent IE, Balmelli C, Meehan B, Allan G, Summerfield A, McCullough KC.
Porcine circovirus type 2 (PCV2) infection of natural interferon producing cells (NIPCs) impairs the induction of interferon (IFN)-alpha and tumour necrosis factor (TNF)-alpha by cytosine-phosphorothioate-guanine (CpG) oligodeoxynucleotides (ODNs), thereby...
发表于Oct 2006: Research in Veterinary Science Volume 81, Issue 2, Pages 287-292
PCR detection of porcine circovirus type 2 (PCV2) DNA in blood, tonsillar and faecal swabs from experimentally infected pigs
A. Caprioli, F. McNeilly, I. McNair, P. Lagan-Tregaskis, J. Ellis, S. Krakowka, J. McKillen, F. Ostanello and G. Allan
PCV2 infection is now recognized as the major factor in the development of post-weaning multisystemic wasting syndrome (PMWS). In this study we evaluated the use of PCR to detect the presence of PCV2 DNA in blood, faecal and tonsillar swabs collected...
发表于Oct 2006: J. Gen. Virol., 87: 2923 - 2932
Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence
T. Opriessnig, N. E. McKeown, E.-M. Zhou, X.-J. Meng and P. G. Halbur
There are marked differences in the clinical expression of diseases associated with porcine circovirus type 2 (PCV2) in the field. The objective of this study was to compare the sequences and pathogenicity of PCV2 isolates from field cases with and without...
发表于Oct 2006: Can J Vet Res. 2006 Oct;70(4):269-76
The role of immunostimulation in the development of postweaning multisystemic wasting syndrome in pigs under field conditions.
Haruna J, Hanna P, Hurnik D, Ikede B, Miller L, Yason C.
We evaluated the effects of immunostimulation in the development of postweaning multisystemic wasting syndrome (PMWS) in 930 pigs 53 to 54 d old in a grower/finisher barn with a history of PMWS. The pigs were allocated to 5 treatment groups: 4 groups...
