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第24号公告板 - Spring 2006
VirologyPMWS-Circovirus-PDNS
LOPEZ-SORIA S, SEGALES J, NOFRARIAS M, SIBILA M, ESPINAL A, RAMIREZ H, MINGUEZ A, SERRANO JM, MARIN O, JOISEL F, CHARREYRE C
PCV2 infection dynamics in two farms: relationship with PMWS expression, mortality and weight.
International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology, 2005
The aim of this study was to compare the effect of two prorcine circovirus type 2 (PCV2) infection dynamics on postweaning multisystemic wasting syndrome (PMWS). The study took place in two similar Spanish farms, free from porcine reproductive and respiratory syndrome virus (PRRSV) and from Aujeszky's disease virus. Weaned pigs were selected in both farms (517 in the first farm and 545 in the second farm). From 3 to 21 weeks of age, the mortality rate was determined in all pigs. In parallel, blood samples were collected and weigh measured in 207 selected pigs. All pigs that died during the postweaning period were necropsied. Polymerase chain reaction (PCR) and immunoperoxidase monolayer assay (IPMA) techniques were used to determine the presence of PCV2 genome and antibody titers against PCV2, respectively. Chi-square or Fisher's exact tests were use dto determine the viremia, seroconversion, weight and postweaning mortality associated with PMWS. It was shown that an earlier and more persistent infection resulted in a higher postweaning mortality and a more sever PMWS presentation.
