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第21号公告板 - Spring 2005
VirologyPorcine Reproductive and Respiratory Syndrome (PRRS)
VAN GUCHT S, LABARQUE G, VAN REETH K
The combination of PRRS virus and bacterial endotoxin as a model for multifactorial respiratory disease in pigs.
Veterinary Immunology and Immunopathology, 2004, Volume 102, Nº3, 165-178
PRRSV and LPS were demonstrated to have a synergic action regarding the induction of proinflammatory cytokines. Such overproduction of cytokines was associated with disease. The PRRSV-LPS combination is thus suggested as a reproducible model to study the pathogenesis of multifactorial respiratory disease in pigs.
