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第19号公告板 - Fall 2004
18th IPVS Congress, Hamburg, Germany, 2004Porcine Reproductive and Respiratory Syndrome (PRRS)
JUILLARD V, PIRAS F, ANDREONI C, CHARREYRE C, JOISEL F
PPRSV-specific and persistent TH1 cell response in pigs following PRRSV infection and/or vaccination with an inactivated PRRS vaccine
Proceedings of the 18th IPVS Congress, Hamburg, Germany, 2004 - Volume 1:137
A protocol based on the use of Progressis® (Merial) and including 3 groups of 7 pigs was designed as follows: group 1 was not vaccinated and kept as control, group 2 was vaccinated at D0 and D21, group 3 was vaccinated at D42 and D57, all 3 groups were challenged with an homologous PRRSV strain at D35. PRRSV-specific IFNγ+ T cell responses were monitored by a porcine IFNγ-ELISpost assay. Interestingly, the magnitude of PRRSV-specific IFNγ+ T cell responses was not affected by PRRSV challenge suggesting that even in a contaminated environment vaccination with Progressis® provides a substantial and persistent PRRSV-specific IFNγ+ T cell response in pigs.
