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第16号公告板 - Fall 2003
VirologyPMWS-Circovirus-PDNS
NUNEZ A, MCNEILLY F, PEREA A, SANCHEZ-CORDON PJ, HUERTA B, ALLAN G, CARRASCO L
Coinfection by Cryptosporidium parvum and porcine circovirus type 2 in weaned pigs.
Journal of Veterinary Medicine. B, 2003, Volume 50, n?5, 255-258
A 3-month-old diarrheic piglet was investigated. A massive infestation by Cryptosporidium parvum was diagnosed. However, lesions typical of PCV2 infection were observed and PCV2 infection was confirmed by immunohistochemistry. Unexpectedly, cytoplasmic inclusion bodies were detected in foci of histiocytic infiltrates in jejunum submucosa. In addition, a close association between histiocytic cells and eosinophils was observed. The virus was particularly abundant in the areas where parasites were more numerous. PCV2 is known to induce systemic lymphoid depletion and create an immunosuppression state. Therefore, PCV2 may have paved the way for C. parvum which is usually rare in post-weaning and growing pigs.
