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第16号公告板 - Fall 2003
Fourth International Symposium on Emerging and Re-emerging Pig diseasesPMWS-Circovirus-PDNS
LAROCHELLE R, MAGAR R, D'ALLAIRE S
Comparative serological and virological study of herds with and without postweaning multisystemic wasting syndrome (PMWS).
Proceedings of the 4th International Symposium on Emerging and Re-emerging Pig Diseases, 2003, 226-227
Even if PMWS implies PCV2, PCV2 infection does not necessarily induces PMWS. Three experimental models have been demonstrated to trigger PMWS in PCV2-infected pigs: co-infection with porcine parvovirus (PPV), co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and immunostimulation. Yet to date, no field study could provide information of that kind regarding PMWS/PCV2 field reality. Kinetics of PCV2 infection and sequence of PCV2 in PMWS and non-PMWS herds were investigated as well as the presence of PPV, PRRSV and the use of immunomodulating agents (vaccines). No difference either in the kinetics of PCV2 infection nor in the genomic sequence of PCV2 strains between PMWS and non-PMWS was determined. No link between either PMWS and co-infection with PPV or PRRSV nor PMWS and immunostimulation could be established. The triggering mechanisms of PMWS need to further investigated.
